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Slc22a1 Antibody / Oct1

CAT: 0800-RQ7253Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ7253Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Solute carrier family 22 (organic cation transporter), member 1, also called SLC22A1 or OCT1 (Organic cation transporter 1) is a protein that in humans is encoded by the SLC22A1 gene. This gene is mapped to 6q25.3. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene transports the polyamines spermine and spermidine. It also transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. This gene regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
O08966
Host
Rabbit
Reactivity
Mouse
Immunogen
Amino acids QKRTTQAVRIMEQIAQKNRK were used as the immunogen for the Slc22a1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Slc22a1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Slc22a1 antibody is available for research use only.
Storage Conditions
After reconstitution, the Slc22a1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Slc22a1 antibody should be determined by the researcher.
Image Legend
Western blot testing of mouse HEPA1-6 cell lysate with Slc22a1 antibody. Predicted molecular weight ~61 kDa but this glycoprotein may be observed at up to ~80 kDa.

UniProtKB · O08966

Solute carrier family 22 member 1

S22A1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
O08966
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Slc22a1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9R1Q4
Protein keywords

Cellular component

Cell membraneMembrane

PTM

GlycoproteinPhosphoprotein

Biological process

Ion transportTransport

Technical term

Reference proteome

Domain

TransmembraneTransmembrane helix
Product Datasheet
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