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Azido-PEG4-alpha-D-mannose

CAT: 0804-HY-141126-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-141126-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Azido-PEG4-alpha-D-mannose is a PEG linker that combines an azide group with an alpha-D-mannose moiety. Azido-PEG4-alpha-D-mannose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Azido-PEG4-alpha-D-mannose has the targeting property of mannose, which can accurately deliver drugs to specific cells or tissues to improve the therapeutic effect of drugs[1].
CAS Number
1632372-86-1
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/azido-peg4-alpha-d-mannose.html
Purity
96.24
Solubility
H2O : 250 mg/mL (ultrasonic)
Smiles
O[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@H]1OCCOCCOCCOCCN=[N+]=[N-]
Molecular Formula
C14H27N3O9
Molecular Weight
381.38
References & Citations
[1]Shaodong Zhang, et al. Mimicking biological membranes with programmable glycan ligands self-assembled from amphiphilic Janus glycodendrimers. Angew Chem Int Ed Engl. 2014 Oct 6;53 (41) :10899-903.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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