Azido-PEG4-Thiol

CAT: 0804-HY-138525-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-138525-01Size:5 mg
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Description
Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-Thiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
CAS Number
[2720615-82-5]
UNSPSC
12352211
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/azido-peg4-thiol.html
Purity
78.86
Solubility
10 mM in DMSO
Smiles
SCCOCCOCCOCCOCCN=[N+]=[N-]
Molecular Formula
C10H21N3O4S
Molecular Weight
279.36
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

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