5,7-Dihydroxychromone (Standard)

5,7-Dihydroxychromone (Standard)

• CAS Number: 31721-94-5
• UNSPSC Description: 5,7-Dihydroxychromone (Standard) is the analytical standard of 5,7-Dihydroxychromone. This product is intended for research and analytical applications. 5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1].
• Target Antigen: Arenavirus; Caspase; Keap1-Nrf2; PARP
• Type: Reference Standards
• Related Pathways: Anti-infection;Apoptosis;Cell Cycle/DNA Damage;Epigenetics;NF-κB
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/5-7-dihydroxychromone-standard.html
• Smiles: O=C1C=COC2=CC(O)=CC(O)=C12
• Molecular Weight: 178.14
• References & Citations: [1]Kim DW, et al. Neuroprotection against 6-OHDA-induced oxidative stress and apoptosis in SH-SY5Y cells by 5,7-Dihydroxychromone: Activation of the Nrf2/ARE pathway. Life Sci. 2015 Jun 1;130:25-30.
• Shipping Conditions: Room temperature