5,7-Dihydroxychromone

• Target :

  Nrf2|||PARP|||Caspase|||Anti-infection|||Virus Protease

• Related Pathways :

  Immunology/Inflammation|||Proteases/Proteasome|||Apoptosis|||DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Microbiology/Virology

• Purity :

  0.9976

• Bioactivity :

  1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating Nrf2/ARE signal . 3. 5,7-Dihydroxychromone induces the translocation of Nrf2 to the nucleus and increases Nrf2/ARE binding activity which results in the up-regulation of the expression of Nrf2-dependent antioxidant genes, including HO-1, NQO1, and GCLc.

• Smiles :

  Oc1cc(O)c2c(c1)occc2=O

• Molecular Formula :

  C9H6O4

• Molecular Weight :

  178.14

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  31721-94-5