5,7-Dihydroxychromone

CAT: 0931-MF-0012079-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0012079-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
31721-94-5
Target
Nrf2|||PARP|||Caspase|||Anti-infection|||Virus Protease
Related Pathways
Immunology/Inflammation|||Proteases/Proteasome|||Apoptosis|||DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Microbiology/Virology
Purity
0.9976
Bioactivity
1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating Nrf2/ARE signal . 3. 5,7-Dihydroxychromone induces the translocation of Nrf2 to the nucleus and increases Nrf2/ARE binding activity which results in the up-regulation of the expression of Nrf2-dependent antioxidant genes, including HO-1, NQO1, and GCLc.
Smiles
Oc1cc(O)c2c(c1)occc2=O
Molecular Formula
C9H6O4
Molecular Weight
178.14
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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