TRAF6 Recombinant Rabbit Monoclonal Antibody [JE01-42]

TRAF6 Recombinant Rabbit Monoclonal Antibody [JE01-42]

• Description: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/TRANCE/RANKL and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported.
• Product Name Alternative: E3 ubiquitin-protein ligase TRAF6 antibody Interleukin 1 signal transducer antibody Interleukin-1 signal transducer antibody MGC 3310 antibody MGC:3310 antibody MGC3310 antibody OTTHUMP00000232772 antibody OTTHUMP00000232773 antibody RING finger protein 85 antibody RNF 85 antibody RNF85 antibody TNF receptor associated factor 6 antibody TNF receptor-associated factor 6 antibody TNF receptor-associated factor 6, E3 ubiquitin protein ligase antibody TRAF 6 antibody Traf6 antibody TRAF6_HUMAN antibody
• Abbreviation: TRAF6, RNF85
• CAS Number: 9000-83-3
• Swiss Prot: Q9Y4K3 Human, P70196 Mouse, B5DF45 Rat
• Cellular Locus: Cytoplasm, cell cortex, Nucleus, Lipid droplet.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within
• Isotype: IgG
• Clone: JE01-42
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, FC
• Positive Control: K-562 cell lysate, 293T cell lysate, HeLa cell lysate, COS-1 cell lysate, CTLL-2 cell lysate, RAW264.7 cell lysate, PC-12 cell lysate, PC-12, HeLa, RAW264.7.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IF-Cell: 1:100 ;FC: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 60 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes