Products for Research Use Only

(-) -Maackiain (Standard)

CAT: 0804-HY-N6051RSize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N6051RSize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(-​) ​-Maackiain (Standard) is the analytical standard of (-​) ​-Maackiain. This product is intended for research and analytical applications. (-) -Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-) -Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-) -Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-) -Maackiain is orally active[1][2].
CAS Number
2035-15-6
UNSPSC
12352005
Target
Fungal; NF-κB; NOD-like Receptor (NLR) ; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Immunology/Inflammation; NF-κB; Others
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/maackiain-standard.html
Smiles
OC1=CC=C([C@@]2([H])[C@@](C3=C(C=C4C(OCO4)=C3)O2)([H])CO5)C5=C1
Molecular Formula
C16H12O5
Molecular Weight
284.26
References & Citations
[1]ScottSoby, et al. Detoxification of the phytoalexins maackiain and medicarpin by fungal pathogens of alfalfa. Phytochemistry. 1996 Feb;14 (3) :759-765.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
No Development Reported