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Maackiain

CAT: 0804-HY-N0381-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0381-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Maackiain (DL-Maackiain) is isolated from Maackia amurensis Rupr.et Maxim. Maackiain (DL-Maackiain) is a larvicidal agent against Aedes aegypti mosquito.xp Parasitol with a LD50 of 21.95 µg/mL[1]. Maackiain (DL-Maackiain) induces fragmentations of DNA to oligonucleosomal-sized fragments that like a characteristic of apoptosis in the HL-60 cells[2].
CAS Number
19908-48-6
Product Name Alternative
DL-​Maackiain
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/maackiain-1.html
Purity
99.83
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
OC1=CC=C2OC[C@]3([H])C4=CC5=C(OCO5)C=C4O[C@]3([H])C2=C1
Molecular Formula
C16H12O5
Molecular Weight
284.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Bezerra-Silva PC, et al. Extract of Bowdichia virgilioides and maackiain as larvicidal agent against Aedes aegypti mosquito.xp Parasitol. 2015 Jun;153:160-4.|[2]Aratanechemuge Y, et al. Induction of apoptosis by maackiain and trifolirhizin (maackiain glycoside) isolated from sanzukon (Sophora Subprostrate Chen et T. Chen) in human promyelotic leukemia HL-60 cells.Oncol Rep. 2004 Dec;12 (6) :1183-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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