EG-2184

• Description:

  EG-2184 is a Pannexin-1 channel inhibitor. EG-2184 can be used in opioid withdrawal related research[1].

• UNSPSC:

  12352005

• Target:

  Gap Junction Protein

• Type:

  Reference compound

• Related Pathways:

  Cytoskeleton

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/eg-2184.html

• Purity:

  99.50

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=S(C1=CC=C(C(C(F)(F)F)(C(F)(F)F)O)C=C1)(N(CCC)CCC)=O

• Molecular Formula:

  C15H19F6NO3S

• Molecular Weight:

  407.37

• References & Citations:

  [1]Kwok CHT, et al. Pannexin-1 channel inhibition alleviates opioid withdrawal in rodents by modulating locus coeruleus to spinal cord circuitry. Nat Commun. 2024 Jul 24;15 (1) :6264.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2770297-66-8]