Products for Research Use Only
RegisterLogin

Lovastatin-d9

CAT: 0804-HY-N0504S1-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0504S1-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Lovastatin-d9 is the deuterium labeled Lovastatin. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.
Product Name Alternative
Mevinolin-d9
UNSPSC
12352005
Target
Autophagy; Ferroptosis; HMG-CoA Reductase (HMGCR) ; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease; Cancer
Purity
99.04
Solubility
10 mM in DMSO
Smiles
O=C(O[C@H]1C[C@H](C=C2C=C[C@H](C)[C@@H]([C@]21[H])CC[C@H]3OC(C[C@@H](C3)O)=O)C)C(C([2H])([2H])[2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
Molecular Formula
C24H27D9O5
Molecular Weight
413.60
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Alberts AW, et al. Discovery, biochemistry and biology of lovastatin. Am J Cardiol. 1988 Nov 11;62 (15) :10J-15J.|[3]Kah J, et al. Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression. Oncol Rep. 2012 Sep;28 (3) :1077-83.|[4]Frishman WH, et al. Lovastatin: an HMG-CoA reductase inhibitor for lowering cholesterol. Med Clin North Am. 1989 Mar;73 (2) :437-48.|[5]Tobert JA, et al. Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors. Nat Rev Drug Discov. 2003 Jul;2 (7) :517-26.|[6]Ifergan I, et al. Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis. Ann Neurol. 2006 Jul;60 (1) :45-55.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N0504-01Lovastatin
HY-169818Keto lovastatin
HY-N0504R-01Lovastatin (Standard)
HY-N0504S2Lovastatin-d3
HY-122439Lovastatin acid
HY-N0504S-01Epi lovastatin-d3
HY-143802SLovastatin hydroxy-d3 (ammonium)
HY-123672-01Lovastatin hydroxy acid (sodium)
HY-123672S-01Lovastatin-d3 hydroxy acid (sodium)
HY-123672RLovastatin hydroxy acid (sodium) (Standard)

Alternative Products

CatalogName
AR-L01998-01Lovastatin-d9
453921Lovastatin-d9 (Mixture of Diastereomers)
sc-491447Lovastatin-d9 Hydroxy Acid Sodium Salt
453922Lovastatin-d9 Hydroxy Acid Sodium Salt (Mixture of Diastereomers)
51R-U370600Lovastatin

Popular Products