2’-O-Methyl-5’-O-DMTr-5-iodouridine

CAT:

804-HY-W342904

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CAS Number: 588691-24-1
UNSPSC Description: 2’-O-Methyl-5’-O-DMTr-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Reference compound
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/2-o-methyl-5-o-dmtr-5-iodouridine.html
Solubility: 10 mM in DMSO
Smiles: COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](O)[C@@H](OC)[C@H](N5C(NC(C(I)=C5)=O)=O)O4
Molecular Weight: 686.49
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-W342904	2’-O-Methyl-5’-O-DMTr-5-iodouridine
HY-W340190-02	2'-O-Methyl-5-iodouridine
HY-W340190-01	2'-O-Methyl-5-iodouridine
HY-W340190-03	2'-O-Methyl-5-iodouridine
HY-154490	5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-uridine
HY-154581	5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-cytidine
HY-154080	5'-O-DMTr-2'-FU-methyl phosphonamidite
HY-154081	5’-O-DMTr-2’-OMeU-methyl phosphonamidite
HY-154684	5-Benzylamino carbonyl-3’-O-acetyl-2’-O-methyl-5’-O-DMTr-uridine
HY-154211	5'-O-DMTr-dU-methyl phosphonamidite