5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-cytidine

• UNSPSC Description:

  5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/5-furan-2-yl-2-o-methyl-5-o-dmtr-cytidine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC(C(C1=CC=CO1)=CN2[C@H]3[C@H](OC)[C@H](O)[C@@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)O3)=NC2=O

• Molecular Weight:

  625.67

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2095417-02-8