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Heteropodatoxin-2 (TFA)

CAT: 0804-HY-P5785A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P5785A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Heteropodatoxin-2 (TFA), a peptides of 30-amino acid, is a heteropodatoxin. Heteropodatoxin-2 blocks Kv4.2 current expressed in Xenopus laevis oocytes in a voltage-dependent manner, with less block at more positive potentials[1].
UNSPSC
12352209
Target
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/heteropodatoxin-2-tfa.html
Purity
97.08
Solubility
H2O : ≥ 50 mg/mL
Smiles
O=C([C@@H](N)CC(O)=O)N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC3=CNC4=CC=CC=C34)=O)CC(O)=O)=O)CC(C)C)=O)CCCCN)=O)=O)CC(O)=O)=O)C)=O)CC(N)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)CSSC[C@H](NC5=O)C(N[C@H](C(N[C@H](C(N[C@H]2CC6=CNC7=CC=CC=C67)=O)CC(C)C)=O)CCCNC(N)=N)=O)=O)=O)CO)=O)CC8=CC=CC=C8)=O)CC(C)C)=O)CCCCN)=O)=O)CSSC[C@H](NC1=O)C(N[C@H](C(NCC(N[C@H](C(N[C@H]5C(C)C)=O)CC9=CC=C(O)C=C9)=O)=O)CCC(O)=O)=O)=O)CC(O)=O.O=C(C(F)(F)F)O.[x]
Molecular Formula
C144H207N39O46S6.xC2HF3O2
Molecular Weight
3412.81 (free base)
References & Citations
[1]M C Sanguinetti, et al. Heteropodatoxins: peptides isolated from spider venom that block Kv4.2 potassium channels. Mol Pharmacol. 1997 Mar;51 (3) :491-8.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported

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