Products for Research Use Only
RegisterLogin

Heteropodatoxin-1

CAT: 0804-HY-P5786Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P5786Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Heteropodatoxin-1 (HpTx1), a spider peptide toxin, is a Kv4.2 current inhibitor. Heteropodatoxin-1 also inhibits Nav1.7 and activates Nav1.9 but does not affect Nav1.8[1].
Product Name Alternative
HpTx1
UNSPSC
12352209
Target
Potassium Channel; Sodium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/heteropodatoxin-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@H]3CCCCN)=O)=O)=O)=O)NC4=O)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](CC7=CNC=N7)C(N[C@@H](CC8=CC=C(C=C8)O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@H]9CC(C)C)=O)=O)=O)=O)NC3=O)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@H]4CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CC%10=CC=C(C=C%10)O)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(O)=O)C(N[C@@H](CC%11=CNC%12=CC=CC=C%11%12)C(N)=O)=O)=O)=O)=O)=O)=O)NC9=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N
Molecular Formula
C168H238N46O51S6
Molecular Weight
3910.35
References & Citations
[1]Xi Zhou, et al. Spider venom-derived peptide induces hyperalgesia in Nav1.7 knockout mice by activating Nav1.9 channels. Nat Commun. 2020 May 8;11 (1) :2293.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P5785Heteropodatoxin-2
HY-P5785A-01Heteropodatoxin-2 (TFA)
HY-N6838-011,1,1,1-Kestohexaose
HY-157129AMPK-α1β1γ1 activator 1
HY-1336231,1,1-Tribromoacetone
HY-149536TWIK-1/TREK-1-IN-1
HY-W160628S1,1,1-Trimethoxypropane-d5
HY-133630-011-Bromo-1,1-dichloroacetone
HY-W881439-011- (1,1-Dimethylethyl) tridecanedioate
HY-W032015S11-Bromooctane-1,1-d2

Alternative Products

CatalogName
MBS5822094Heteropodatoxin-1
T80434-01Heteropodatoxin-2
OF59775-011,1,1,1,1-Kestoheptaose
N2864-5.11,1,1,1-Kestohexaose
1120401,1,1,1-Kestohexose
410417-011,1,1-Trichloromethanesulfonic Acid 1,1'-Anhydride
IFA69273-011-Iodobicyclo[1.1.1]pentane

Popular Products