PAD2-IN-2 (TFA)

• Description:

  PAD2-IN-2 (cis-isomer of 1) TFA is a protein arginine deiminase 2 (PAD2) inhibitor. PAD2-IN-2 TFA possess an azobenzene photoswitch to optically control PAD activity. PAD2-IN-2 TFA inhibits histone H3-citrullination[1].

• UNSPSC:

  12352005

• Target:

  Protein Arginine Deiminase

• Related Pathways:

  Epigenetics

• Field of Research:

  Cancer

• Smiles:

  O=C(C1=CC=C(C=C1)/N=N\C2=CC=CC=C2)N[C@H](C3=NC4=CC=CC=C4N3)CCCNC(CCl)=N.O=C(O)C(F)(F)F

• Molecular Formula:

  C28H27ClF3N7O3

• Molecular Weight:

  602.01

• References & Citations:

  [1]Santanu Mondal, et al. Photochemical Control of Protein Arginine Deiminase (PAD) Activity. ACS Chem Biol. 2018 Apr 20;13 (4) :1057-1065.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported