Endomorphin 2 (TFA)

• Description :

  Endomorphin 2 TFA, a high affinity, highly selective agonist of the μ-opioid receptor, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM[1].

• UNSPSC :

  12352209

• Target :

  Opioid Receptor

• Type :

  Peptides

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/endomorphin-2-tfa.html

• Purity :

  99.04

• Solubility :

  DMSO : < 1 mg/mL|H2O : 125 mg/mL (ultrasonic)

• Smiles :

  O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CC2=CC=CC=C2)NC([C@H]3N(C([C@H](CC4=CC=C(C=C4)O)N)=O)CCC3)=O)=O.OC(C(F)(F)F)=O

• Molecular Formula :

  C34H38F3N5O7

• Molecular Weight :

  685.69

• References & Citations :

  [1]Goldberg IE, et al. Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. J Pharmacol Exp Ther. 1998 Aug;286 (2) :1007-13.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• Isoform :

  μ Opioid Receptor/MOR

• CAS Number :

  [1276124-00-5]