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O-304

CAT: 0804-HY-112233-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-112233-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
O-304 is a first-in-class, orally available pan-AMPK activator, which increases AMPK activity by suppressing the dephosphorylation of pAMPK. O-304 exhibits a great potential as a agent to treat type 2 diabetes (T2D) and associated cardiovascular complications [1][2].
CAS Number
1261289-04-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/O-304.html
Purity
99.59
Solubility
DMSO : 30 mg/mL (ultrasonic; warming)
Smiles
O=C(NC(SN1CC2=CC=C(Cl)C=C2)=NC1=O)C3=CC=C(Cl)C=C3
Molecular Formula
C16H11Cl2N3O2S
Molecular Weight
380.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Periodic Reporting for period 1-AMPK-DIAB (A small molecule AMP activated protein kinase (AMPK) activator, denoted O304, as a novelinnovative drug for the treatment of type 2 diabetes) .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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Alternative Products

CatalogName
BA4625-25O-304
CS-O-58165O-304-d6
A19807-100O-304 100mg
A19807-50O-304 50mg
A19807-5O-304 5mg
A19807-500O-304 500mg
A19807-1O-304 1mg
A19807-25O-304 25mg

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