Products for Research Use Only

12-Ethyl-9-hydroxycamptothecin

CAT: 0804-HY-N2063-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N2063-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1].
CAS Number
119577-28-5
UNSPSC
12352005
Hazard Statement
H301
Target
Topoisomerase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/12-ethyl-9-hydroxycamptothecin.html
Purity
99.89
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(O)C=CC(CC)=C5N=C4C3=C2)=O
Molecular Formula
C22H20N2O5
Molecular Weight
392.40
Precautions
H301
References & Citations
[1]Luzzio MJ, et al. Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I. J Med Chem. 1995;38 (3) :395-401.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported