Products for Research Use Only
RegisterLogin

Cys-mc-MMAE

CAT: 0804-HY-157284-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-157284-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cys-mc-MMAE is a Drug-Linker Conjugates for ADC, and consists of Monomethyl auristatin E and a linker. Cys-mc-MMAE can be used for synthesis of ADCs[1].
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cys-mc-mmae.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC[C@@H]([C@H](N(C)C([C@@H](NC([C@@H](N(C)C(CCCCCN1C(C(CC1=O)SC[C@@H](C(O)=O)N)=O)=O)C(C)C)=O)C(C)C)=O)[C@H](OC)CC(N2[C@H]([C@H](OC)[C@H](C(N[C@@H]([C@H](C3=CC=CC=C3)O)C)=O)C)CCC2)=O)C
Molecular Formula
C52H85N7O12S
Molecular Weight
1032.34
References & Citations
[1]Wang Y, et al. Antibody-Drug Conjugate Using Ionized Cys-Linker-MMAE as the Potent Payload Shows Optimal Therapeutic Safety. Cancers (Basel) . 2020 Mar 21;12 (3) :744.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported

Related Products

CatalogName
HY-171822-01Cys-MC-VC-PAB-MMAE
HY-15741-01Mc-MMAE
HY-154915-01MC-EVCit-PAB-MMAE
HY-136317-01MC-betaglucuronide-MMAE-1
HY-171060-01Mc-Pro-PAB-MMAE
HY-147239-01MC-VA-PABC-MMAE
HY-136321MC-betaglucuronide-MMAE-2
HY-176415-01Cys-MC-GGFG-Dxd
HY-153428-01GGGDTDTC-Mc-vc-PAB-MMAE
HY-141833-01Bi-Mc-VC-PAB-MMAE

Alternative Products

CatalogName
T87843-01Cys-mc-MMAE
T205812-01Cys-MC-VC-PAB-MMAE
T18312-01Mc-MMAE
A21089-100Mc-MMAE 100mg
A21089-25Mc-MMAE 25mg
A21089-1Mc-MMAE 1mg
A21089-50Mc-MMAE 50mg
A21089-10Mc-MMAE 10mg
A21089-5Mc-MMAE 5mg
BA2641-5MC-VA-PABC-MMAE

Popular Products