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JNJ-40413269

CAT: 0804-HY-120481Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120481Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNJ-40413269 is an inhibitor for FAAH, that inhibits human FAAH and rats FAAH with IC50 of 28 nM and 270 nM. JNJ-40413269 exhibits analgesic efficacy in rat spinal nerve ligation model and exhibits good pharmacokinetic characteristics in rats[1].
CAS Number
1184847-16-2
UNSPSC
12352005
Target
FAAH
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jnj-40413269.html
Smiles
FC(F)(F)C1=CC=C(C2=NC=NC(NC[C@H](O)C3=CC=CC=C3)=C2)C=C1Cl
Molecular Formula
C19H15ClF3N3O
Molecular Weight
393.79
References & Citations
[1]Keith JM, et al., 1-Aryl-2- ((6-aryl) pyrimidin-4-yl) amino) ethanols as competitive inhibitors of fatty acid amide hydrolase. Bioorg Med Chem Lett. 2014 Mar 1;24 (5) :1280-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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