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(Rac) -Ganoderic acid C2

CAT: 0804-HY-N1517A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1517A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(Rac) -Ganoderic acid C2 is the racemate of Ganoderic acid C2. Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses anti-tumor, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM[[1][2].
CAS Number
98296-48-1
UNSPSC
12352211
Target
Aldose Reductase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-ganoderic-acid-c2.html
Smiles
O=C(C(CC(CC(C1CC(C2(C)C3=C(C4(CCC(C(C)(C4CC3O)C)O)C)C(CC12C)=O)O)C)=O)C)O
Molecular Formula
C30H46O7
Molecular Weight
518.68
References & Citations
[1]Guo XY, et al. l characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2013 Mar 5;75:64-73. |[2]Fatmawati S, et al. Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. Planta Med. 2010 Oct;76 (15) :1691-3.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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