Hydroxy Itraconazole

• Product Name Alternative:

  Itraconazole metabolite Hydroxy Itraconazole; R-63373

• UNSPSC Description:

  Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

• Target Antigen:

  Drug Metabolite; Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/Itraconazole-metabolite-Hydroxy-Itraconazole.html

• Purity:

  99.74

• Solubility:

  DMSO : 83.33 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL

• Smiles:

  O=C(N(N=C1)C(C)C(O)C)N1C(C=C2)=CC=C2N(CC3)CCN3C(C=C4)=CC=C4OC[C@H](CO5)O[C@@]5(C6=C(C=C(C=C6)Cl)Cl)CN7C=NC=N7

• Molecular Weight:

  721.63

• References & Citations:

  [1]Mino Y, et al. Hydroxy-itraconazole pharmacokinetics is similar to that of itraconazole in immunocompromised patients receiving oral solution of itraconazole. Clin Chim Acta. 2013 Jan 16;415:128-32.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  112559-91-8