Hydroxy Itraconazole

CAT: 0804-HY-12772-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-12772-01Size:5 mg
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Description
Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
CAS Number
[112559-91-8]
Product Name Alternative
Itraconazole metabolite Hydroxy Itraconazole; R-63373
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite; Fungal
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Itraconazole-metabolite-Hydroxy-Itraconazole.html
Purity
99.80
Solubility
DMSO : 83.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
O=C(N(N=C1)C(C)C(O)C)N1C(C=C2)=CC=C2N(CC3)CCN3C(C=C4)=CC=C4OC[C@H](CO5)O[C@@]5(C6=C(C=C(C=C6)Cl)Cl)CN7C=NC=N7
Molecular Formula
C35H38Cl2N8O5
Molecular Weight
721.63
Precautions
H302, H315, H319, H335
References & Citations
[1]Mino Y, et al. Hydroxy-itraconazole pharmacokinetics is similar to that of itraconazole in immunocompromised patients receiving oral solution of itraconazole. Clin Chim Acta. 2013 Jan 16;415:128-32.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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