Hydroxy Itraconazole

• Description :

  Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

• Product Name Alternative :

  Itraconazole metabolite Hydroxy Itraconazole; R-63373

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Drug Metabolite; Fungal

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/Itraconazole-metabolite-Hydroxy-Itraconazole.html

• Purity :

  99.80

• Solubility :

  DMSO : 83.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

• Smiles :

  O=C(N(N=C1)C(C)C(O)C)N1C(C=C2)=CC=C2N(CC3)CCN3C(C=C4)=CC=C4OC[C@H](CO5)O[C@@]5(C6=C(C=C(C=C6)Cl)Cl)CN7C=NC=N7

• Molecular Formula :

  C35H38Cl2N8O5

• Molecular Weight :

  721.63

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Mino Y, et al. Hydroxy-itraconazole pharmacokinetics is similar to that of itraconazole in immunocompromised patients receiving oral solution of itraconazole. Clin Chim Acta. 2013 Jan 16;415:128-32.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [112559-91-8]