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AXKO-0046

CAT: 0804-HY-147216-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-147216-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AXKO-0046, indole derivative, is an uncompetitive Lactate dehydrogenase B (LDHB) selective inhibitor.AXKO-0046 has LDHB inhibitory activity with an EC50 value of 42 nM.AXKO-0046 can be used for the research of cancer metabolism[1].
UNSPSC
12352005
Target
Lactate Dehydrogenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/axko-0046.html
Purity
99.77
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C1(NCC(N2)=C(CCNCC3=CC=CC=C3)C4=C2C=CC=C4)CCCCCC1
Molecular Formula
C25H33N3
Molecular Weight
375.55
References & Citations
[1]Sachio Shibata, et al. Identification of the first highly selective inhibitor of human lactate dehydrogenase B. Sci Rep. 2021 Nov 1;11 (1) :21353.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LDHB

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