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Otilonium (bromide) (Standard)

CAT: 0804-HY-B0499AR-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0499AR-01Size:5 mg
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Description
Otilonium (bromide) (Standard) is the analytical standard of Otilonium (bromide) . This product is intended for research and analytical applications. Otilonium bromide (OB) is an orally active mAChR inhibitor and smooth muscle relaxant which can interfere with the mobilization of calcium in intestinal smooth muscle, OB can be used for research of irritable bowel syndrome[1][2][3].
CAS Number
26095-59-0
Product Name Alternative
Octylonium bromide (Standard) ; SP63 (Standard)
UNSPSC
12352005
Target
MAChR; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/otilonium-bromide-standard.html
Smiles
O=C(OCC[N+](CC)(CC)C)C1=CC=C(NC(C2=CC=CC=C2OCCCCCCCC)=O)C=C1.[Br-]
Molecular Formula
C29H43BrN2O4
Molecular Weight
563.57
References & Citations
[1]Battaglia, G., et al., Otilonium bromide in irritable bowel syndrome: a double-blind, placebo-controlled, 15-week study. Aliment Pharmacol Ther, 1998. 12 (10) : p. 1003-10.|[2]Gandia, L., et al., Otilonium: a potent blocker of neuronal nicotinic ACh receptors in bovine chromaffin cells. Br J Pharmacol, 1996. 117 (3) : p. 463-470.|[3]Lindqvist S, et al. The colon-selective spasmolytic otilonium bromide inhibits muscarinic M (3) receptor-coupled calcium signals in isolated human colonic crypts. Br J Pharmacol. 2002 Dec;137 (7) :1134-42.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

CatalogName
T1474-01Otilonium bromide
AR-O01568-01Otilonium-d4 Bromide
MBS6068991-01Octylonium Bromide (Spasmonen. Otilonium Bromide)
CS-O-58910Otilonium-d3 Bromide
AR-O01573-01Otilonium Bromide Impurity 5
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RM-O200902-01Otilonium Bromide Impurity 2

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