Products for Research Use Only
RegisterLogin

NNMT-IN-5

CAT: 0804-HY-161316Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-161316Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NNMT-IN-5 (Compound 3-12) is a potent nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 47.9 ± 0.6 nM) . NNMT-IN-5 also has an excellent selectivity profile over a panel of human methyltransferases. NNMT-IN-5 can be used for the research of cancer, diabetes, metabolic disorders, and neurodegenerative diseases[1].
UNSPSC
12352005
Target
Amine N-methyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nnmt-in-5.html
Solubility
10 mM in DMSO
Smiles
N[C@H](C(O)=O)CCN(CC#CC1=CC=CC(C(N)=O)=C1)C[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=C(CC)C4=C3N=CN=C4N)O2
Molecular Formula
C27H33N7O6
Molecular Weight
551.59
References & Citations
[1]Li P, et al. Enhancing nicotinamide N-methyltransferase bisubstrate inhibitor activity through 7-deazaadenosine and linker modifications. Bioorg Chem. 2024 Feb;143:106963.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-151193NNMT-IN-3
HY-151813-01NNMT-IN-4
HY-W1006754NNMT-IN-7
HY-132890NNMT-IN-2
HY-138993-01NNMT-IN-6
HY-138993A-01NNMT-IN-6 (hydrochloride)
HY-P88088NNMT Antibody (YA7772, Mouse)
HY-P701318-01Nicotinamide N-Methyltransferase/NNMT, Human (GST)
HY-RS16748Nnmt Mouse Pre-designed siRNA Set A
HY-RS09395NNMT Human Pre-designed siRNA Set A

Alternative Products

CatalogName
T209371-01NNMT-IN-5
ant-615NNMT
039036NNMT, ID (NNMT, Nicotinamide N-methyltransferase)
10R-5021NNMT antibody
512120NNMT discontinued
MBS5823313NNMT-IN-4
OPPA02222-5UGNNMT Protein
TS400641P5NNMT CytoSection

Popular Products