DBCO-Biotin
CAT:
804-HY-123916-02
Size:
50 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DBCO-Biotin
- CAS Number: 1418217-95-4
- UNSPSC Description: DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Target Antigen: PROTAC Linkers
- Type: Reference compound
- Related Pathways: PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/dbco-biotin.html
- Purity: 98.49
- Solubility: DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C1N[C@](CS2)([H])[C@@](N1)([H])[C@@H]2CCCCC(NCCC(N3C4=CC=CC=C4C#CC5=CC=CC=C5C3)=O)=O
- Molecular Weight: 502.63
- References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported