AVE-9488

• Description :

  AVE-9488 is an eNOS enhancer with the activity of protecting the heart from ischemia-reperfusion injury. AVE-9488 can upregulate eNOS expression, increase NO production, reduce myocardial ischemia-reperfusion injury, and reduce the level of reactive oxygen species[1].

• UNSPSC :

  12352005

• Target :

  NO Synthase

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/ave-9488.html

• Purity :

  99.77

• Solubility :

  DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(NC1CC2=C(C=CC=C2)C1)C3=CC=C(F)C=C3

• Molecular Formula :

  C16H14FNO

• Molecular Weight :

  255.29

• References & Citations :

  [1]The eNOS enhancer AVE 9488: a novel cardioprotectant against ischemia reperfusion injury

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  ENOS

• CAS Number :

  [291756-32-6]