AVE-9488

• Description:

  AVE-9488 is an eNOS enhancer with the activity of protecting the heart from ischemia-reperfusion injury. AVE-9488 can upregulate eNOS expression, increase NO production, reduce myocardial ischemia-reperfusion injury, and reduce the level of reactive oxygen species[1].

• UNSPSC:

  12352005

• Target:

  NO Synthase

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ave-9488.html

• Purity:

  99.77

• Solubility:

  DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(NC1CC2=C(C=CC=C2)C1)C3=CC=C(F)C=C3

• Molecular Formula:

  C16H14FNO

• Molecular Weight:

  255.29

• References & Citations:

  [1]The eNOS enhancer AVE 9488: a novel cardioprotectant against ischemia reperfusion injury

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  ENOS

• CAS Number:

  [291756-32-6]