AVE-5997

• Description :

  AVE-5997 is a selective b>D3 antagonist. AVE-5997 antagonizes MK-801 (HY-15084B) -induced hyperactivity. AVE-5997 can be used in the research of schizophrenia[1].

• UNSPSC :

  12352005

• Target :

  Dopamine Receptor

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Smiles :

  O=C(NCCCCN1CCN(C2=CSC3=CC(C(F)(F)F)=CC=C32)CC1)NC4=CC=C(C)C=C4

• Molecular Formula :

  C25H29F3N4OS

• Molecular Weight :

  490.58

• References & Citations :

  [1]Zhang M, et al. Effect of dopamine D3 antagonists on PPI in DBA/2J mice or PPI deficit induced by neonatal ventral hippocampal lesions in rats. Neuropsychopharmacology. 2006 Jul;31 (7) :1382-92.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• Isoform :

  D3 Receptor

• CAS Number :

  [452917-21-4]