5-Hydroxytryptophol (Standard)
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5-Hydroxytryptophol (Standard)
Description:
5-Hydroxytryptophol is a mammalian serotonin metabolite that can be used as a sensitive biomarker for recent alcohol intake. 5-Hydroxytryptophol is formed by alcohol-induced changes in the serotonin metabolic pathway and is excreted in the urine as a glucuronic acid conjugate. 5-Hydroxytryptophol is elevated in urine excretion and can be used clinically to monitor alcohol intake in scenarios such as alcohol relapse[1][2].UNSPSC:
12352005Target:
Endogenous MetaboliteRelated Pathways:
Metabolic Enzyme/ProteaseField of Research:
Metabolic DiseaseSmiles:
OC1=CC2=C (NC=C2CCO) C=C1Molecular Formula:
C10H11NO2Molecular Weight:
177.20References & Citations:
[1]Beck O, et al. 5-hydroxytryptophol as a marker for recent alcohol intake. Addiction. 2003 Dec;98 Suppl 2:63-72.|[2]Eccleston D, et al. The formation of 5-hydroxytryptophol in brain in vitro. Br J Pharmacol Chemother. 1966 Dec;28 (3) :367-77.Shipping Conditions:
Room temperatureScientific Category:
Reference StandardsCAS Number:
154-02-9
