Br-Boc-C2-azido

CAT: 0804-HY-138464-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-138464-01Size:100 mg

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Description

Br-Boc-C2-azido is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Br-Boc-C2-azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

CAS Number

1120364-53-5

UNSPSC

12352211

Hazard Statement

H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/br-boc-c2-azido.html

Solubility

10 mM in DMSO

Smiles

CC(C)(Br)C(OCCN=[N+]=[N-])=O

Molecular Formula

C6H10BrN3O2

Molecular Weight

236.07

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers

Chemical Information

Br-Boc-C2-azido

CAS Number	1120364-53-5
PubChem CID	86650124
IUPAC Name	2-azidoethyl 2-bromo-2-methylpropanoate
Molecular Formula	C6H10BrN3O2
Molecular Weight	236.07
XLogP	2.4
Topological Polar Surface Area	40.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Heavy Atom Count	12
Formal Charge	0
Complexity	211

SMILES

CC(C)(C(=O)OCCN=[N+]=[N-])Br

InChI

InChI=1S/C6H10BrN3O2/c1-6(2,7)5(11)12-4-3-9-10-8/h3-4H2,1-2H3

InChIKey

OYSXPOJKJKBNSG-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1120364-53-5

CID: 86650124

Formula: C6H10BrN3O2

MW: 236.07

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	236.07
XLogP3	2.4
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Exact Mass	234.99564
Monoisotopic Mass	234.99564
Topological Polar Surface Area	40.7 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	211
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-130315-01	Br-PEG4-C2-Boc
HY-130483-01	Br-PEG3-C2-Boc
HY-140776-01	Azido-PEG2-C2-Boc
HY-140779-01	Azido-PEG6-C2-Boc
HY-138406-01	Boc-NH-PEG8-C2-Br
HY-138474	Boc-PEG1-PPG2-C2-azido
HY-W957364	Pomalidomide-C2-Br
HY-176188	Lenalidomide-5-Br-amide-C2-Br
HY-138358-01	Azido-PEG23-C2-azide
HY-W131504	Boc-C14-Br

Alternative Products

Catalog	Name
T38505	Br-Boc-C2-azido
GTR19215908-01	Br-PEG3-C2-Boc
GTR19215906-01	Br-PEG4-C2-Boc
GTR19226647-01	Azido-PEG6-C2-Boc
T17493-01	Azido-PEG2-C2-Boc
T210416-01	Boc-NH-PEG8-C2-Br
T207998-01	Boc-PEG1-PPG2-C2-azido
GTR19241053-01	Pomalidomide-C2-Br
T207503-01	Lenalidomide-5-Br-amide-C2-Br
GTR19276328-01	Boc-C14-Br

Br-Boc-C2-azido

Chemical Information

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