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CD5 (Mantle Cell LymphomaMarker)

CAT: 0544-MBS4380734-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
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CAT#:0544-MBS4380734-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[CD5]
NCBI Gene ID
921
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a mature T-cell neoplasms. Anti-CD5 detection is in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
Other Gene Names
[CD5; CD5; T1; LEU1; LEU1]
Short Name
[CD5]
Other Product Names
[T-cell surface glycoprotein CD5 isoform 2; T-cell surface glycoprotein CD5; T-cell surface glycoprotein CD5; CD5 molecule; Lymphocyte antigen T1/Leu-1; CD_antigen: CD5]
NCBI GI Number
1080078688
NCBI Accession Number
NP_001333385.1
NCBI GB Accession Number
NM_001346456.1
Uniprot Accession Number
P06127

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