TLE1 (Synovial Sarcoma Marker)
CAT:
544-MBS4380502-04
Size:
5x 0.1 mg (With BSA & Azide at 0.2mg/mL)
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TLE1 (Synovial Sarcoma Marker)
- Gene Name: [TLE1]
- NCBI Gene ID: 7088
- Reactivity: Human. Others not known.
- Specificity: Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.
- Other Gene Names: [TLE1; TLE1; ESG; ESG1; GRG1; ESG1]
- Short Name: [TLE1]
- Other Product Names: [transducin-like enhancer protein 1 isoform 1; Transducin-like enhancer protein 1; transducin-like enhancer protein 1; transducin like enhancer of split 1; E(Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1]
- NCBI GI Number: 733605268
- NCBI Accession Number: NP_001290032.1
- NCBI GB Accession Number: NM_001303103.1
- Uniprot Accession Number: Q04724