Calnexin (Endoplasmic Reticulum Marker)

Calnexin (Endoplasmic Reticulum Marker)

• Gene Name: [CANX]
• NCBI Gene ID: 821
• Reactivity: Human. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: It recognizes a protein of 90kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. 
• Other Gene Names: [CANX; CANX; CNX; P90; IP90]
• Short Name: [Calnexin]
• Other Product Names: [calnexin isoform d; Calnexin; calnexin; calnexin; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90]
• NCBI GI Number: 66933005
• NCBI Accession Number: NP_001019820.1
• NCBI GB Accession Number: NM_001024649.1
• Uniprot Accession Number: P27824