Anti-Calnexin (Endoplasmic Reticulum Marker) (CANX/1543), CF594 conjugate
CAT:
37-BNC941543-500
Size:
500 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-Calnexin (Endoplasmic Reticulum Marker) (CANX/1543), CF594 conjugate
- Description: Calnexin is a type-I integral membrane protein of the endoplasmic reticulum (ER). It is a calcium-binding chaperone protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation._x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_
- Synonyms: Calnexin; CANX; IP90; Major histocompatibility complex class I antigen-binding protein p88
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: CANX
- Gene ID: 821
- NCBI Gene ID: 567968
- UniProt: P27824
- Cellular Locus: Endoplasmic reticulum
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300) (exact sequence is proprietary)
- Target Antigen: Calnexin
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Clone: CANX/1543
- Conjugation: CF594
- Source: Animal
- Applications: IHC, FFPE (verified) | WB (verified)
- Validated Applications: IHC, FFPE, WB
- Field of Research: Chaperones, Immunology
- Positive Control: HeLa, MCF-7 or U2OS cells. Kidney or small intestine.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 67 kDa (predicted); 80-90 kDa (observed)
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years