IMP-2373

• Description:

  IMP-2373 is the activity-based probe (ABP) . IMP-2373 is a covalent pan- deubiquitinase (DUB) ABP to monitor DUB activity in physiologically relevant live cells[1].

• UNSPSC:

  12171500

• Target:

  Deubiquitinase; Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Cell Cycle/DNA Damage; Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/imp-2373.html

• Purity:

  99.58

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  C#CC1=CC=C(CNC(C2=CC(C(C3CN(C#N)CC3)=O)=CN2C)=O)C=C1

• Molecular Formula:

  C21H20N4O2

• Molecular Weight:

  360.41

• References & Citations:

  [1]Daniel Conole, et al. Discovery of a Potent Deubiquitinase (DUB) Small-Molecule Activity-Based Probe Enables Broad Spectrum DUB Activity Profiling in Living Cells. Angew Chem Int Ed Engl. 2023, 62, 47.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported