AGEN-2373

• Target:

  TNF

• Related Pathways:

  Apoptosis

• Bioactivity:

  AGEN-2373 is a conditional agonist antibody targeting the costimulatory receptor CD137. It binds to CD137 without interfering with ligand binding. AGEN-2373 stimulates CD137 under receptor clustering conditions and can enhance T-cell activity when used with other checkpoint modulators (e.g., PD-1 antagonists and OX40 agonists) . AGEN-2373 is used in human malignancy research.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C