IMP-1088

• UNSPSC Description:

  IMP-1088 is a potent human N-myristoyltransferases NMT1 and NMT2 dual inhibitor with IC50s of Kd of rhinovirus replication by blocking rhinovirus virus-encoded protein (VP0) N-myristoylation. IMP-1088 protects host cells from the cytotoxic effects of viral infection[1].

• Target Antigen:

  DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/imp-1088.html

• Purity:

  99.16

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CN1N=C(CN(C)C)C2=C1C=CC(C3=CC=C(F)C(F)=C3OCCC4=C(C)N(C)N=C4C)=C2

• Molecular Weight:

  453.53

• References & Citations:

  [1]Aurélie Mousnier, et al. Fragment-derived Inhibitors of Human N-myristoyltransferase Block Capsid Assembly and Replication of the Common Cold Virus. Nat Chem. 2018 Jun;10(6):599-606.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2059148-82-0