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PMGT1 rabbit pAb

CAT: 0855-ES14054-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES14054-01Size:50 µL
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Background
This gene encodes a type II transmembrane protein that resides in the Golgi apparatus. It participates in O-mannosyl glycosylation and is specific for alpha linked terminal mannose. Mutations in this gene may be associated with muscle-eye-brain disease and several congenital muscular dystrophies. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Feb 2014]
Description
This gene encodes a type II transmembrane protein that resides in the Golgi apparatus. It participates in O-mannosyl glycosylation and is specific for alpha linked terminal mannose. Mutations in this gene may be associated with muscle-eye-brain disease and several congenital muscular dystrophies. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Feb 2014],
UniProt
Q8WZA1
Swiss Prot
Q8WZA1
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human PMGT1 AA range: 171-221
Target
PMGT1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Golgi apparatus membrane ; Single-pass type II membrane protein .
Gene ID (Human)
55624

UniProtKB · Q8WZA1

Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

PMGT1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8WZA1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POMGNT1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
POMGnT1
EC number
2.4.1.-
Processing
—
Secondary accessions
D3DQ16, Q5VST2, Q5VST3, Q9BV55, Q9H9L8, Q9NXF9, Q9NYF7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Congenital muscular dystrophyDisease variantDystroglycanopathyLimb-girdle muscular dystrophyLissencephalyRetinitis pigmentosa

PTM

Disulfide bondPhosphoprotein

Molecular function

GlycosyltransferaseTransferase

Cellular component

Golgi apparatusMembrane

Ligand

LectinManganeseMetal-binding

Domain

Signal-anchorTransmembraneTransmembrane helix

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