SCH 60057

• Description:

  SCH 60057 (Compound 7) is a neurokinin (NK) receptor inhibitor that can be isolated from Acremonium sp., with IC50 values of 6 μM and 12 μM for NK1 and NK2, respectively[1].

• UNSPSC:

  12352211

• Target:

  Neurokinin Receptor

• Type:

  Natural Products

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sch-60057.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCCC(C)(O)CCCC(C)(O)CCCC(C)(O)CCCC(C)(O)CCCC(C)(O)CC/C=C(C)\C

• Molecular Formula:

  C45H84O6

• Molecular Weight:

  721.14

• References & Citations:

  [1]Hegde VR, et al. Neurokinin receptor inhibitors: fermentation, isolation, physico-chemical properties, structure and biological activity. J Antibiot (Tokyo) . 1997 Dec;50 (12) :983-91.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [203061-35-2]