SPC-alkyne

• UNSPSC Description:

  SPC-alkyne (compound 9) is an alkynyl derivative. SPC-alkyne suppresses IL-2 production and AP-1 and NFAT reporters[1].

• Target Antigen:

  Interleukin Related

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/spc-alkyne.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C#CC1=CC=C(N=C(C2=CC=CS2)N=C3NN4C(C=C(C)C4=O)=O)C3=C1

• Molecular Weight:

  360.39

• References & Citations:

  [1]Chen YF, et al. Targeting the chromatin binding of exportin-1 disrupts NFAT and T cell activation. Nat Chem Biol. 2024 Mar 25.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported