SPC 839 (Standard)
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SPC 839 (Standard)
Description :
SPC 839 (Standard) is the analytical standard of SPC 839 (HY-10072) . This product is intended for research and analytical applications. SPC 839 (compound 10) is an orally active inhibitor of AP-1 and NF-kB mediated transcriptional activation with IC50 of 0.008 μM[1].Target :
AP-1; NF-κB; Reference StandardsRelated Pathways :
Immunology/Inflammation; NF-κB; OthersField of Research :
Inflammation/ImmunologySmiles :
O=C(C(C)=C1)N(NC2=C(C(OC)=CC=C3)C3=NC(C4=CC=CS4)=N2)C1=OMolecular Formula :
C18H14N4O3SMolecular Weight :
366.39References & Citations :
[1]Moorthy S S Palanki, et al. The design and synthesis of novel orally active inhibitors of AP-1 and NF-kappaB mediated transcriptional activation. SAR of in vitro and in vivo studies. Bioorg Med Chem Lett. 2003 Nov 17;13 (22) :4077-80.Shipping Conditions :
Room temperatureScientific Category :
Reference StandardsCAS Number :
[219773-55-4]

