Reverse T3

CAT: 0804-HY-W010696-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W010696-01Size:5 mg
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Description
Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine[1]. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes[2].
CAS Number
[5817-39-0]
Product Name Alternative
3′,5′,3-Triiodothyronine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/reverse-t3.html
Concentration
10mM
Purity
97.97
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
IC(C=C(C=C1)C[C@H](N)C(O)=O)=C1OC2=CC(I)=C(C(I)=C2)O
Molecular Formula
C15H12I3NO4
Molecular Weight
650.97
Precautions
H302, H315, H319, H335
References & Citations
[1]Nicod P, et al. Radioimmunoassay for 3,3',5'-triiodo-L-thyronine in unextracted serum: method and clinical results. J Clin Endocrinol Metab. 1976 May;42 (5) :823-9. |[2]Rebolledo RA, et al. Anti-Apoptotic Effects of 3,3',5-Triiodo-L-Thyronine in the Liver of Brain-Dead Rats. PLoS One. 2015 Oct 5;10 (10) :e0138749. |[3]Verga Falzacappa C, et al. 3,5,3'-triiodothyronine (T3) is a survival factor for pancreatic beta-cells undergoing apoptosis. J Cell Physiol. 2006 Feb;206 (2) :309-21.|[4]Bronson Kumar Khangembam, et al. Effect of cortisol and triiodothyronine bath treatments on the digestive enzyme profile and growth of atla catla larvae during ontogenic development, Aquaculture Research.13054, 48, 5, (2173-2185), (2016) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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