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T3 Peptide

CAT: 0804-HY-P10320Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10320Size:1 Each
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Description
T3 Peptide is an active fragment of tumstatin. T3 Peptide binds integrin αvβ3/αvβ5, activates the PI3K/Akt/p70S6K signaling pathway, and thus stimulates the proliferation and migration of rat cardiac fibroblasts[1].
Product Name Alternative
Tumstatin (69-88), human
UNSPSC
12352209
Target
Akt; PI3K
Type
Peptides
Related Pathways
PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/t3-peptide.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N)CC(C)C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2C(C)C)=O)CC(O)=O)=O)CC(N)=O)=O)C(C)C)=O)CC(N)=O)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)CC(N)=O)=O)=O)CC4=CC=CC=C4)=O)CC(C)C)=O)CC5=CC=CC=C5)=O)CCC1)=O)CCSC)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CC6=CC=CC=C6)=O)CCCNC(N)=N)=O)CCC(N)=O
Molecular Formula
C109H159N27O29S3
Molecular Weight
2407.79
References & Citations
[1]Yasuda J, et al., T3 peptide, a fragment of tumstatin, stimulates proliferation and migration of cardiac fibroblasts through activation of Akt signaling pathway. Naunyn Schmiedebergs Arch Pharmacol. 2017 Nov;390 (11) :1135-1144.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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