T3 Peptide

• UNSPSC Description:

  T3 Peptide is an active fragment of tumstatin. T3 Peptide binds integrin αvβ3/αvβ5, activates the PI3K/Akt/p70S6K signaling pathway, and thus stimulates the proliferation and migration of rat cardiac fibroblasts[1].

• Target Antigen:

  Akt; PI3K

• Type:

  Peptides

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/t3-peptide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H](N)CC(C)C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2C(C)C)=O)CC(O)=O)=O)CC(N)=O)=O)C(C)C)=O)CC(N)=O)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)CC(N)=O)=O)=O)CC4=CC=CC=C4)=O)CC(C)C)=O)CC5=CC=CC=C5)=O)CCC1)=O)CCSC)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CC6=CC=CC=C6)=O)CCCNC(N)=N)=O)CCC(N)=O

• Molecular Weight:

  2407.79

• References & Citations:

  [1]Yasuda J, et al., T3 peptide, a fragment of tumstatin, stimulates proliferation and migration of cardiac fibroblasts through activation of Akt signaling pathway. Naunyn Schmiedebergs Arch Pharmacol. 2017 Nov;390(11):1135-1144.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported