Reverse transcriptase-IN-3

CAT: 0804-HY-151938Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-151938Size:1 Each
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Description
Reverse transcriptase-IN-3 is a pyrimidine-5-carboxamide derivative, acts as an inhibitor of HIV-1. Reverse transcriptase-IN-3 shows potent activity against the HIV-1 wild-type and mutant strains[1].
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/reverse-transcriptase-in-3.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(C#N)=CC(C)=C1OC2=C(C=NC(NC3CCN(CC3)C4=CC=C(C=C4)NS(=O)(C5CC5)=O)=N2)C(N)=O
Molecular Formula
C28H31N7O4S
Molecular Weight
561.66
References & Citations
[1]Feng D, et al. Disubstituted pyrimidine-5-carboxamide derivatives as novel HIV-1 NNRTIs: Crystallographic overlay-based molecular design, synthesis, and biological evaluation. Eur J Med Chem. 2022 Nov 22;246:114957.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1

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