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RS-25344

CAT: 0804-HY-69172Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-69172Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RS-25344 is a selective inhibitor of phosphodiesterase type IV (PDE4) . RS-25344 increases intracellular cAMP (cyclic adenosine phosphate) concentration by inhibiting PDE4 activity. RS-25344 can be used in the study of inflammation, immune diseases, neurodegenerative diseases and cardiovascular diseases[1].
CAS Number
152814-89-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/rs-25344.html
Smiles
O=C1N(C2=CC=CC([N+]([O-])=O)=C2)C3=NC=CC=C3C(N1CC4=CC=NC=C4)=O
Molecular Formula
C19H13N5O4
Molecular Weight
375.34
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Fisch J D, et al. Enhancement of motility and acrosome reaction in human spermatozoa: differential activation by type-specific phosphodiesterase inhibitors[J]. Human Reproduction (Oxford, England), 1998, 13 (5) : 1248-1254.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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