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Imperatoxin A (TFA)

CAT: 0804-HY-P3037A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P3037A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Imperatoxin A TFA is a peptide toxin derived from the venom of the African scorpion Pandinus imperator. Imperatoxin A TFA is a Ca2+-release channels/ryanodine receptors (RyRs) activator. Imperatoxin A TFA enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell[1].
UNSPSC
12352209
Target
Calcium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/imperatoxin-a-tfa.html
Purity
98.65
Solubility
H2O : ≥ 100 mg/mL
Smiles
O=C(CN)N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2CSSC[C@H](NC3=O)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)CC(O)=O)=O)CC(N)=O)=O)CC(O)=O)=O)C)=O)CCCCN)=O)CSSC[C@H](NC4=O)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]3CCCNC(N)=N)=O)CCCCN)=O)CCC(O)=O)=O)C)=O)CC(N)=O)=O)[C@@H](C)O)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCCN)=O)=O)CCCNC(N)=N)=O)CCCCN)=O)CC(C)C)=O)CC5=CNC=N5)=O)CCC1)=O)CC(C)C)=O)CSSC[C@H](NC2=O)C(NCC(N[C@H](C(N[C@H]4CCCCN)=O)CCCCN)=O)=O)=O)CC(O)=O.O=C(O)C(F)(F)F.[x]
Molecular Formula
C148H254N58O45S6.xC2HF3O2
Molecular Weight
3758.35 (free base)
References & Citations
[1]Georgina B Gurrola, et al. Imperatoxin A, a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca2+-Release Channels/Ryanodine Receptors. Pharmaceuticals (Basel) . 2010 Apr 1;3 (4) :1093-1107.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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