MARK-IN-1

CAT: 0804-HY-101933-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-101933-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MARK-IN-1 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of <0.25 nM.
CAS Number
[1109283-93-3]
UNSPSC
12352005
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/MARK-IN-1.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C2=C3N=CC(C4=CN(C)N=C4)=CN3N=C2)=C(C)S1)N[C@H]5C(F)(F)CCC[C@H]5N
Molecular Formula
C22H23F2N7OS
Molecular Weight
471.53
References & Citations
[1]Sloman DL, et al. Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties. Bioorg Med Chem Lett. 2016 Sep 1;26 (17) :4362-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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