MARK-IN-2
CAT:
804-HY-101934-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MARK-IN-2
- CAS Number: 1314893-26-9
- UNSPSC Description: MARK-IN-2 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of 5 nM.
- Target Antigen: AMPK; MARK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Epigenetics;PI3K/Akt/mTOR
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/MARK-IN-2.html
- Purity: 99.19
- Solubility: DMSO : 25 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC(C2=C3N=CC(Cl)=CN3N=C2)=C(C)S1)N[C@H]4C(F)(F)CCC[C@H]4N
- Molecular Weight: 425.88
- References & Citations: [1]Sloman DL, et al. Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4362-6.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported