CFI-400936

CAT: 0804-HY-123675Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-123675Size:1 Each
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Description
CFI-400936 is a potent TTK inhibitor with an IC50 of 3.6 nM. CFI-400936 has antitumor activity[1].
CAS Number
[1338793-07-9]
UNSPSC
12352005
Target
Mps1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cfi-400936.html
Smiles
O=C(C(N(C)C)C1=C(CC)C=CC=C1)NC2=CC3=C(NN=C3C4=CC(S(=O)(N)=O)=CC=C4)C=C2
Molecular Formula
C25H27N5O3S
Molecular Weight
477.58
References & Citations
[1]Laufer R, et al. Discovery of inhibitors of the mitotic kinase TTK based on N- (3- (3-sulfamoylphenyl) -1H-indazol-5-yl) -acetamides and carboxamides. Bioorg Med Chem. 2014 Sep 1;22 (17) :4968-97.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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