RegisterLogin

CFI-401980

CAT: 0804-HY-120032Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-120032Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CFI-401980 is a selective tyrosine threonine kinase MPS1 inhibitor with a Ki of 0.8 nM. CFI-401980 inhibits the proliferation of HCT116 cell lines. CFI-401980 can be studied in anti-cancer research[1].
CAS Number
[1610676-27-1]
UNSPSC
12352005
Target
Mps1
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(NC1CC1)C2=CC=C(C3=C4N(N=C3)C(NCC5CCOCC5)=NC(OC6=CC=CC=C6)=N4)C=C2C
Molecular Formula
C28H30N6O3
Molecular Weight
498.58
References & Citations
[1]Laufer, R., et al., (2016) . Discovery of 4- (4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl) benzamides as novel, highly potent and selective, orally bioavailable inhibitors of Tyrosine Threonine Kinase, TTK. Bioorganic & medicinal chemistry letters, 26 (15), 3562-3566.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-116190CFI-401870
HY-120279ACFI-400437
HY-123675CFI-400936
HY-P88426CFI Antibody (YA8110, Mouse)
HY-132135-01(1E) -CFI-400437 (dihydrochloride)
HY-RS20677Cfi Mouse Pre-designed siRNA Set A
HY-RS02567CFI Human Pre-designed siRNA Set A
HY-RS27188Cfi Rat Pre-designed siRNA Set A
HY-124099SCH 40120

Alternative Products

CatalogName
T30805-01CFI-401980
521453-01CFI
EMk27563Monkey CFI (CFI) ELISA Kit
MBS8588187-01CFI Antibody
T22645-01CFI-400945
T30804-01CFI-401870
BUP03723-01CFI-402257
T70940-01CFI-400936
GW2058-1mgCFI-400437
32-13754-10CFI Human

Popular Products